Mucociliary Respiratory Epithelium Integrity in Molecular Defense and Susceptibility to Pulmonary Viral Infections
Mucociliary defense, mediated by the ciliated and goblet cells, is fundamental to respiratory fitness.The concerted action of ciliary movement on the respiratory epithelial surface and the pathogen entrapment function of mucus help to maintain healthy airways.Consequently, genetic or acquired defects in lung defense elicit respiratory diseases and